Venus Fully Automated Cell Counter

Venus is a full-automatic portable high-throughput cell counter introduced by Newton Optics, which can count all kinds of cells in high-throughput bright field and trypan blue. Venus adopts split design and EasyFive six-digit cell counting plate, which can realize accurate counting of 6 samples and 30 visual fields in one step, and the time is only 1 minute. The unique portable design greatly improves the space utilization of the laboratory.

Venus is a full-automatic portable high-throughput cell counter introduced by Newton Optics, which can count all kinds of cells in high-throughput bright field and trypan blue. Venus adopts split design and EasyFive six-digit cell counting plate, which can realize accurate counting of 6 samples and 30 visual fields in one step, and the time is only 1 minute. The unique portable design greatly improves the space utilization of the laboratory.

Patented fully automatic/autofocus cell viability analysis system * 
Venus uses Newtonian optical self-developed automatic cell viability analysis control scheme, with stepper motor and joystick control sample entry, movement and precise positioning, the use of high-speed camera to obtain images, combined with analysis software, complete cell count analysis. At the same time, thanks to the inverted microscopic imaging optical path design and compact automatic focusing mobile structure *,Venus has achieved a technological breakthrough of smaller size and higher degree of automation. Fully automated design brings less human factor errors, thereby improving experimental efficiency and accuracy.
* A new automatic cell counter. ZL 202020922280.2 (Authorized)
* A compact electric focusing moving structure for inverted microscopic imaging. ZL 202021861178.2 (Authorized)


 

Stable, high-speed, high-throughput image analysis technology 
The Venus cell counter uses a high-pixel industrial-grade CMOS sensor. In the counting process, each sample is sampled in 5 fields of view, and the average value is automatically calculated. A larger sample collection volume ensures the accuracy of the count. It is verified that the R2 value of the counting result fitting is greater than 0.999 *. At the same time, with the integrated control system and efficient algorithm, compared with the traditional blood cell counting board manual counting 1 × 106 cells takes about 5 minutes, Venus cell counting instrument only takes 2 seconds. In 1 minute, accurate results * for 6 samples and 30 sampling fields can be obtained *.
* Results from cell count tests on RAW264.7,Siha at gradient concentrations, respectively
* Results from a single six-sample fully automated test of suspension culture cells at a concentration of 1 × 106


 

Fully self-developed artificial intelligence algorithm 
As the key technology of cell counter, intelligent image recognition and analysis algorithm determines the accuracy and stability of the counting results. Venus cell counter uses Newton optical self-developed artificial intelligence algorithm. After testing and verification, for the same sample, the CV value of single field count is less than 10%, and the CV value of multi-field count is less than 5%. In addition, Newton optics is specially optimized for small diameter, high density, cluster cells, cell debris and other special cell samples, which greatly broadens the scope of application of the cell counter. And, Newton optics will continue to optimize the algorithm design, software free iterative upgrade, suitable for more cell system.
 

Humanized interactive interface 
The Venus cell counter must be used with a computer *. The user can freely select the analysis mode and adjust the analysis settings (bright field/trypan blue counting mode, specify the sample, adjust the dilution concentration). The software provides detailed data such as analysis result chart, concentration, activity rate, diameter distribution, etc. for users to view and export. A variety of export formats are optional to meet the needs of different users. In addition, the software provides historical data traceability and user rights management * to meet FDA 21 CFR Part 11 regulatory requirements.
* Recommended configuration: i5 CPU, 4G memory, 64GB hard disk, 1024*768 resolution, Windows10 system or above
* Hierarchical permissions function, only administrator users can operate user rights management, including new users, delete users
EasyFive cell counting plate 
Patented six-cell counting board *, high-throughput design, single-chip counting board can count 6 samples, disposable consumables design eliminates cleaning troubles, saves time, avoids cross-contamination, and reduces the biological hazard risk of samples to laboratory personnel. 100 μm/200μm specifications are optional *,100μm counting plate is suitable for high concentration or small diameter cells, and 200μm counting plate is suitable for all kinds of common cells.
* A cell counting special sample pool and preparation method. ZL 201910136771.6 (Submitted)
* Two kinds of counting plate specifications are available, the sampling volume of 100μm counting plate is 14μL, and the sampling volume of 200μm counting plate is 25μL






 

Wide cellular applicability 
At present, we have carried out practical tests on a large number of cells, including suspension culture cells, adherent culture cells, PBMC cells, mammalian cells, insect cells and human cells. The verified cell lines include A549, BHK, CHO, Hek293, Hela, Hepg2, human T cell, Jukat, K562, MCF7, MSC, PBMC, SW62, Vero, etc.