Organoid culture


In the workflow of organoid research, Newtonian optical cell counters, cell fluorescence analyzers, and ultra fast volume bioprinters can play a role in multiple stages, solving the pain points and concerns of users.


1. Early stage of organoid construction - cell count and vitality assessment:
-User pain points: In the early stages of organoid construction, it is necessary to accurately count and evaluate the vitality of cells to ensure the smooth progress of the construction process.
-Solution: Newton Optics' Venus cell counter can automatically analyze six samples simultaneously within one minute, providing key data such as cell concentration and viability. This high-throughput counting capability not only improves work efficiency, but also reduces human error through automation, ensuring consistency and repeatability of results.


2. Analysis of cell characteristics during organoid culture process:
-User pain points: During the process of organoid culture, researchers need to monitor cell proliferation, apoptosis, cycle and other characteristics to evaluate the developmental status of organoids.
-Solution: Newtonian optical cell fluorescence analyzer, such as Jupiter, can combine dual fluorescence channels to quantitatively analyze cell samples, providing multi-dimensional data such as cell cycle and apoptosis rate. This comprehensive analytical ability helps researchers to gain a deeper understanding of the characteristics of organoids and optimize cultivation conditions.


3. Organ like construction and drug screening - high-throughput production and testing:
-User pain points: In drug screening and organoid construction research, a high-throughput production and testing platform is needed to quickly evaluate the impact of various conditions on organoid construction and function.
-Solution: The ultra fast volume bioprinter can print a large number of organoid spheres, such as 96 samples, in a very short amount of time. This not only greatly saves preparation time and reduces material costs, but also allows researchers to provide personalized medication plans for patients within a week. This high-throughput construction capability, combined with the use of Newton's optical cell counter and fluorescence analyzer, provides strong technical support for drug screening and personalized medicine.


4. Organ quality control - data management and regulatory compliance:
-User pain points: Research and application of organoids require strict regulations, such as FDA 21 CFR Part 11, while ensuring data integrity and traceability.
-Solution: Newtonian optical equipment provides historical data traceability and user permission management functions, ensuring data security and traceability, and meeting regulatory requirements. In addition, the free iterative upgrades and technical support of the software ensure that the device can adapt to constantly changing research needs and regulatory requirements.


In summary, the application of Newtonian optical cell counters, cell fluorescence analyzers, and ultra fast volume bioprinters in the workflow of organoid research not only improves the efficiency and accuracy of experiments, but also solves the pain points and concerns of users in cell counting, characteristic analysis, high-throughput construction, and quality control, providing strong technical support for the research and application of organoids.